Modulation of Hippocampal Acetylcholine Release and Spontaneous Alternation Scores by Intrahippocampal Glucose Injections
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چکیده
منابع مشابه
Modulation of hippocampal acetylcholine release and spontaneous alternation scores by intrahippocampal glucose injections.
Recent evidence indicates that systemic glucose treatment enhances memory while producing a corresponding increase in hippocampal acetylcholine (ACh) output. The present experiments examined whether unilateral intrahippocampal infusions of glucose would enhance spontaneous alternation performance and whether there would be a corresponding increase in ACh output in the ipsilateral and contralate...
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Objective(s) Nicotinic acetylcholine receptors (nAChRs) regulate epileptiform activity and produce a sustained pro-epileptogenic action within the hippocampal slices. In the present study, we investigated the effect of nAChRs on evoked glutamatergic synaptic transmission in area CA3 and CA1 of rat hippocampal slices to identify possible excitatory circuits through which activation of nAChRs pr...
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Introduction Nicotine promotes transmitter release in the brain by a direct action on presynaptic terminals. Pharmacological evidence confirms that this action is mediated by nicotinic acetylcholine receptors (nAChR). The most abundant brain nAChR, the a4B2 subtype, is identified by the binding of tritiated nicotine ([,H]Nic) [ 13. Lesioning and subcellular fractionation studies suggest that th...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1998
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.18-04-01595.1998